DNG in Acoustics 2023 / オーストラリア シドニーで開催されるAcoustics 2023にて「Microfluidic platform using focused ultrasound passing through hydrophobic meshes with jump availability」の発表を行います

2023. 11. 30

We will present our works at Acoustics 2023. See you in Stratford!

デジタルネイチャー研究室は,オーストラリア シドニーで開催される Acoustics 2023 にて,“Microfluidic platform using focused ultrasound passing through hydrophobic meshes with jump availability”の発表を行います.

Official Web: https://acoustics23sydney.org/


[Lecture Session] Microfluidic platform using focused ultrasound passing through hydrophobic meshes with jump availability

Laboratory automation is critical in improving productivity and data quality. Droplet-based microfluidic systems offer a solution that enables parallel handling of small samples with high reconfigurability and scalability. The most common technique is electrowetting-on-dielectric (EWOD), which manipulates droplets by exploiting the imbalance of wetting. However, this method is often limited by biofouling. In our previous study, we proposed a novel microfluidic platform using focused ultrasound passing through a hydrophobic mesh, which reduces the contact area and thus the hydrophobic interactions and electrostatic attractions of biomolecules. Our platform demonstrates the manipulation of protein-rich droplets at concentrations up to 1 mg/ml without the need for any additives. This is a significant improvement over existing EWOD methods which are limited to handling samples with protein concentrations as low as 0.005 mg/ml without additives. Here, we further investigate the influence of protein concentration, pH, and buffers using fluorescence microscopy to determine the effect on the system. Our platform also provides basic functions such as moving, merging, and splitting, as well as superior jumping capabilities. With reduced biofouling and the ability to directly transfer droplets to adjacent devices and multi-step processes, our platform opens up new possibilities for the automation of biology.

Authors: Yusuke Koroyasu*2, Ruchi Gupta1, Tatsuya Yamamoto3, Yoichi Ochiai4, Nobuhiko Nomura3, Tatsuki Fushimi4
1School of Chemistry, University of Birmingham, Edgbaston, Birmingham, United Kingdom; 2Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan; 3Faculty of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibraki, Japan; 4Institute of Library‚ Information and Media Science, University of Tsukuba, Tsukuba, Ibaraki, Japan

Project pageMicrofluidic platform using focused ultrasound passing through hydrophobic meshes with jump availability

Date: Mon, Dec 04 2:00pm – 2:20pm (AEDT) / 12:00pm – 12:20pm (JST)
Location: ROOM C2.1
Check here for more information.


名 称 : デジタルネイチャー研究室
所在地 : 茨城県つくば市春日1-2
指導教員 : 准教授 落合 陽一, 助教 伏見 龍樹
研究内容 : 波動工学、デジタルファブリケーション、人工知能技術を用いた空間研究開発
URL : https://digitalnature.slis.tsukuba.ac.jp/


落合 陽一 Yoichi Ochiai
1987生,2015年東京大学学際情報学府博士課程修了(学際情報学府初の短縮終了),博士(学際情報学).日本学術振興会特別研究員DC1,米国Microsoft ResearchでのResearch Internなどを経て,2015年より筑波大学図書館情報メディア系助教 デジタルネイチャー研究室主宰.2015年,Pixie Dust Technologies.incを起業しCEOとして勤務.2017年から2019年まで筑波大学学長補佐,2017年から大阪芸術大学客員教授,2020年デジタルハリウッド大学特任教授,金沢美術工芸大学客員教授,2021年4月から京都市立芸術大学客員教授を兼務.2017年12月より,ピクシーダストテクノロジーズ株式会社による筑波大学デジタルネイチャー推進戦略研究基盤代表及び准教授を兼務.2020年6月デジタルネイチャー開発研究センター・センター長就任.専門はCG,HCI,VR,視・聴・触覚提示法,デジタルファブリケーション,自動運転や身体制御.

伏見 龍樹 Tatsuki Fushimi


名称 : 筑波大学デジタルネイチャー研究室
Email : contact<-at->digitalnature.slis.tsukuba.ac.jp <-at->を@に置き換えてください